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Investigating the role of striatal direct and indirect pathway spiny projection neurons in a cocaine-induced impairment of goal-directed behavioural control

Temporally specific miRNA expression patterns in the dorsal and ventral striatum of addiction-prone rats

Characterizing changes in the orexin system in models of neuropsychiatric disease

Rapamycin reduces motivated responding for cocaine and alters GluA1 expression in the ventral but not dorsal striatum

Understanding striatal neuroadaptations in addiction-relapse vulnerability

Electrophysiological characteristics of paraventricular thalamic (PVT) neurons in response to cocaine and cocaine- and amphetamine-regulated transcript (CART)

mTORC1 inhibition in the nucleus accumbens 'protects' against the expression of drug seeking and 'relapse' and is associated with reductions in GluA1 AMPAR and CAMKIIα levels

Orexin antagonists for neuropsychiatric disease: progress and potential pitfalls

The role of cocaine- and amphetamine- regulated transcript (CART) and orexin in drug- seeking and addiction-related behaviours

An emerging role for the mammalian target of rapamycin in "pathological" protein translation: relevance to cocaine addiction

Cocaine potentiates excitatory drive in the perifornical/lateral hypothalamus

Insights for developing pharamacological treatments for psychostimulant replapse targeting hypothalamic peptide systems

Down-regulated striatal gene expression for synaptic plasticity-associated proteins in addiction and relapse vulnerable animals

Orexin-1 receptor signalling within the ventral tegmental area, but not the paraventricular thalamus, is critical to regulating cue-induced reinstatement of cocaine-seeking

Propensity to 'relapse' following exposure to cocaine cues is associated with the recruitment of specific thalamic and epithalamic nuclei

Cocaine- and amphetamine-regulated transcript (CART) signaling within the paraventricular thalamus modulates cocaine-seeking behaviour

Dissociation of the effects of MTEP [3-[(2-methyl-1,3-thiazol-4-yl)ethynyl] piperidine] on conditioned reinstatement and reinforcement: comparison between cocaine and a conventional reinforcer

Brief cognitive behavioural interventions for regular amphetamine users: a step in the right direction

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